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Polysorbate (tween)
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Properties
Product Name Polysorbate (Tween)
CAS Number 9005-65-6
Formula C16H32O6
Molar Mass 312.43 g/mol
Pub Chem CID 5284440
Drug Bank DB11338
Chem Spider 4444382
Bioavailability N/A
Protein Binding N/A
Metabolism N/A
Elimination Halflife N/A
FAQ
What is Polysorbate (Tween) and what is it used for?
Polysorbate, also known as Tween, is a nonionic surfactant commonly used in pharmaceuticals, food, Cosmetic, and other industries. It is used to stabilize emulsions, prevent separation of ingredients, and improve the solubility of various compounds in water-based solutions.

How does Polysorbate work in emulsions?
Polysorbate works by reducing the surface tension between oil and water molecules in emulsions. This allows the ingredients to mix more easily and form a stable emulsion without separating.

Is Polysorbate safe to use in cosmetic products?
Yes, Polysorbate is considered safe for use in cosmetic products. It is non-toxic, non-irritating, and non-sensitizing when used in proper concentrations. However, as with any ingredient, it is important to follow recommended usage levels to avoid any potential adverse effects.

What are some common applications of Polysorbate in the pharmaceutical industry?
Polysorbate is commonly used in pharmaceutical formulations as a solubilizer for poorly water-soluble drugs. It helps improve the bioavailability and stability of these drugs, making them easier to administer and more effective.

Can Polysorbate be used in food products?
Yes, Polysorbate is approved for use in food products by regulatory agencies such as the FDA. It is commonly used in baked goods, dairy products, salad dressings, and other food items to improve texture, flavor, and shelf life.

How does Polysorbate differ from other surfactants?
Polysorbate is unique in that it is derived from sorbitol and oleic acid, making it a natural and biodegradable surfactant. Unlike some synthetic surfactants, Polysorbate is less likely to cause skin irritation or environmental harm.

Are there any potential side effects of using Polysorbate?
In general, Polysorbate is well-tolerated by most individuals. However, some people with sensitive skin may experience mild irritation or allergic reactions when using products containing Polysorbate. It is always recommended to perform a patch test before using products with this ingredient.

Can Polysorbate be used in combination with other ingredients?
Yes, Polysorbate is compatible with a wide range of ingredients commonly used in cosmetic, pharmaceutical, and food products. It can be combined with oils, waxes, emollients, and other surfactants to create stable formulations with desired properties.

What are the environmental impacts of using Polysorbate?
Polysorbate is considered to have low environmental impact compared to some other surfactants. It is biodegradable and does not persist in the environment, making it a more sustainable choice for formulators looking to reduce their carbon footprint.

Is Polysorbate suitable for vegan or cruelty-free formulations?
Yes, Polysorbate is suitable for vegan and cruelty-free formulations. It is derived from plant-based sources and is not tested on animals, making it a safe and ethical choice for consumers who prioritize these criteria in their skincare, pharmaceutical, or food products.
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