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Mannitol
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Properties
Product Name Mannitol
CAS Number 69-65-8
Formula C6H14O6
Molar Mass 182.17 g/mol
Pub Chem CID 6251
Drug Bank DB00741
Chem Spider 6016
Bioavailability Not Available
Protein Binding Not Available
Metabolism Minimal
Elimination Halflife Variable
FAQ
What is mannitol and what is it used for?

Mannitol is a type of sugar alcohol that is often used as a sweetener in sugar-free products. However, it also has medical uses as an osmotic diuretic, which means it helps to increase urine production. Mannitol is commonly used to treat conditions such as cerebral edema (swelling of the brain), glaucoma (increased pressure in the eye), and to help flush out toxins in cases of overdose.

How does mannitol work as an osmotic diuretic?

Mannitol works as an osmotic diuretic by drawing water into the kidneys, which increases urine production. This helps to reduce swelling in the brain by decreasing the amount of fluid in the body. By increasing urine output, mannitol can also help to flush out toxins or excess substances in the body, such as in cases of drug overdose or poisoning.

Is mannitol safe to use?

Mannitol is generally considered safe when used as directed by a healthcare professional. However, like any medication, it can cause side effects in some individuals. Common side effects of mannitol may include headache, nausea, vomiting, electrolyte imbalances, and fluid overload. It is important to follow the dosing instructions provided by your doctor to minimize the risk of side effects.

Are there any contraindications or precautions to consider when using mannitol?

Mannitol should not be used in patients who are allergic to the medication or who have certain medical conditions such as severe dehydration, heart failure, or kidney disease. It is important to inform your doctor about any medical conditions you have and any other medications or supplements you are taking before using mannitol. Your doctor will be able to determine if mannitol is safe and appropriate for you to use.

How is mannitol administered?

Mannitol is typically given intravenously (IV) by a healthcare professional in a medical setting, such as a hospital. The dosage and rate of administration will be determined by your doctor based on your specific medical condition and needs. It is important to follow your doctor's instructions carefully and to report any unusual symptoms or side effects during treatment with mannitol.

What should I do if I miss a dose of mannitol?

If you miss a dose of mannitol, it is important to contact your healthcare provider as soon as possible to reschedule the dose. Do not try to "catch up" by taking extra doses of mannitol, as this can increase the risk of side effects or complications. It is important to follow the prescribed dosing schedule to ensure the effectiveness and safety of treatment with mannitol.

Can mannitol be used during pregnancy or breastfeeding?

Mannitol may be used during pregnancy if the benefits outweigh the risks, as determined by a healthcare provider. It is important to discuss the potential risks and benefits of using mannitol during pregnancy with your doctor. It is not known if mannitol passes into breast milk, so women who are breastfeeding should consult with their healthcare provider before using mannitol.

How should mannitol be stored?

Mannitol should be stored at room temperature, away from heat and moisture. It is important to keep mannitol in its original packaging and to protect it from light. Do not freeze mannitol or store it in the bathroom. Keep all medications out of the reach of children and pets.

What should I do if I experience side effects from mannitol?

If you experience any side effects from mannitol, such as severe headache, difficulty breathing, chest pain, or swelling of the face, lips, or tongue, seek immediate medical attention. It is important to report any side effects or symptoms to your healthcare provider, as they may indicate a serious or potentially life-threatening reaction to mannitol. Your doctor can help determine the best course of action to address any side effects you may experience while using mannitol.
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