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Quinine
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Properties
Product Name Quinine
Cas Number 130-95-0
Formula C20H24N2O2
Molar Mass 324.418 g/mol
Pub Chem Cid 3034034
Drug Bank DB00468
Chem Spider 22969
Bioavailability 70-90%
Protein Binding 70-90%
Metabolism Hepatic
Elimination Halflife 10-15 hours
FAQ
What is Quinine?

Quinine is a bitter compound that is extracted from the bark of the cinchona tree. It has been used for centuries to treat malaria and is also found in tonic water.

How is Quinine used today?

Today, Quinine is primarily used to treat and prevent malaria. It is also used off-label to treat nighttime leg cramps and as a bittering agent in tonic water.

Is Quinine safe for consumption?

While Quinine is generally safe when used in small amounts to flavor food and beverages, it can have potentially serious side effects when taken in large doses for medical purposes. It should always be used under the guidance of a healthcare professional.

What are the potential side effects of Quinine?

Some common side effects of Quinine include nausea, vomiting, diarrhea, and headache. In more serious cases, Quinine can cause severe allergic reactions, low blood sugar, and heart arrhythmias.

Are there any drug interactions to be aware of with Quinine?

Yes, Quinine can interact with a number of medications, including blood thinners, antidepressants, and certain antibiotics. It is important to consult with a healthcare provider before taking Quinine if you are on any other medications.

Can Quinine be used during pregnancy or breastfeeding?

Quinine is not recommended for use during pregnancy or breastfeeding unless it is deemed absolutely necessary by a healthcare provider. It can cross the placenta and reach the fetus, potentially causing harm.

Are there any dietary restrictions when taking Quinine?

It is advisable to avoid consuming large amounts of grapefruit or grapefruit juice while taking Quinine, as it can increase the risk of side effects. Otherwise, there are no specific dietary restrictions associated with Quinine.

How should Quinine be stored?

Quinine should be stored in a cool, dry place away from direct sunlight and moisture. It should be kept out of reach of children and pets to prevent accidental ingestion.

What should I do if I miss a dose of Quinine?

If you miss a dose of Quinine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double up on doses to make up for a missed one.

Can Quinine be addictive?

Quinine is not considered to be addictive, as it does not produce feelings of euphoria or physical dependence. However, it should still be used with caution and only as directed by a healthcare provider.
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