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Creatine
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Properties
Product Name Creatine
Cas Number 57-00-1
Formula C4H9N3O2
Molar Mass 131.13 g/mol
Pub Chem Cid 586
Drug Bank DB00148
Chem Spider 567
Bioavailability Approximately 40-60%
Protein Binding Nil
Metabolism Primarily in the liver
Elimination Halflife Approximately 3 hours
FAQ
What is creatine?
Creatine is a naturally occurring compound that plays a key role in the production of energy during high-intensity activities such as weightlifting and sprinting. It is made up of three amino acids – arginine, glycine, and methionine, and is primarily stored in the muscles.

How does creatine work?
Creatine works by increasing the availability of ATP, which is the primary source of energy for muscle contractions. By supplementing with creatine, individuals can increase their muscle creatine stores, allowing them to perform at a higher intensity for longer periods of time.

What are the benefits of taking creatine?
Taking creatine has been shown to increase muscle mass, strength, power, and endurance. It can also help improve performance during high-intensity activities such as weightlifting and sprinting. Additionally, creatine may also have cognitive benefits, as it has been shown to enhance brain function.

Is creatine safe to take?
Creatine is one of the most researched supplements available and has been shown to be safe for most individuals when taken at recommended doses. However, some people may experience gastrointestinal discomfort or muscle cramps when taking creatine. It is important to stay hydrated while taking creatine to reduce the risk of these side effects.

How should creatine be taken?
Creatine is typically taken in a loading phase, where individuals consume a higher dose for the first few days to saturate their muscle stores, followed by a maintenance phase where a lower dose is taken to maintain these levels. It is important to follow the recommended dosing instructions on the product label.

Can creatine help with weight loss?
While creatine is not a weight loss supplement, it may indirectly help with weight loss by increasing muscle mass and strength. This can lead to an increase in overall energy expenditure, helping individuals burn more calories throughout the day.

Who can benefit from taking creatine?
Creatine supplementation can benefit a wide range of individuals, including athletes, bodybuilders, and recreational exercisers looking to improve their performance and strength. It can also benefit older adults looking to maintain muscle mass and strength as they age.

Are there any potential risks associated with taking creatine?
While creatine is generally safe for most individuals, there are some potential risks to be aware of. These include dehydration if not enough water is consumed while taking creatine, as well as potential kidney issues in individuals with pre-existing kidney conditions.

How long does it take to see results from taking creatine?
Most individuals will start to see the benefits of creatine supplementation within the first 1-2 weeks of starting a loading phase. These benefits will continue to increase with consistent use over time, especially when combined with a proper diet and exercise program.

Can creatine be taken with other supplements?
Creatine is safe to take with most other supplements, although it is important to read the labels and consult with a healthcare professional if you have any concerns about potential interactions. Some individuals choose to stack creatine with protein supplements to further enhance muscle growth and recovery.
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