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Citrulline
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Properties
Product Name Citrulline
Cas Number 372-75-8
Formula C6H13N3O3
Molar Mass 175.19 g/mol
Pub Chem Cid 9750
Drug Bank DB00131
Chem Spider 9385
Bioavailability 25%
Protein Binding 0%
Metabolism Intestinal mucosa, kidneys, and liver
Elimination Halflife 1-1.5 hours
FAQ
What is Citrulline?
Citrulline is a non-essential amino acid that is naturally produced in the body. It plays a crucial role in the urea cycle, which helps the body get rid of ammonia, a waste product of protein metabolism. Citrulline is also found in certain foods, such as watermelon.

How does Citrulline work in the body?
Citrulline is converted into another amino acid called arginine in the kidneys. Arginine is then used to produce nitric oxide, a molecule that helps relax blood vessels and improve blood flow. This process is essential for overall cardiovascular health and muscle function.

What are the potential benefits of Citrulline supplementation?
Citrulline supplementation has been linked to several potential benefits, including improved exercise performance, increased endurance, reduced muscle soreness, and enhanced recovery. Some studies have also suggested that Citrulline may help lower blood pressure and improve erectile dysfunction.

Who can benefit from taking Citrulline supplements?
Citrulline supplements are commonly used by athletes and fitness enthusiasts looking to boost their performance and recovery. Individuals with cardiovascular issues or those looking to support healthy blood pressure levels may also benefit from Citrulline supplementation.

How should Citrulline supplements be taken?
Citrulline supplements are typically taken in powder or capsule form. The recommended dosage varies depending on individual needs and goals, but most studies suggest a daily dosage of 6-8 grams for athletic performance and recovery benefits. It is best to consult with a healthcare provider before starting any new supplement regimen.

Are there any potential side effects of Citrulline supplementation?
Citrulline is generally considered safe for most people when taken in appropriate dosages. However, some individuals may experience mild side effects such as gastrointestinal discomfort or allergic reactions. It is essential to follow recommended dosages and consult with a healthcare professional if you have any underlying health conditions.

Can Citrulline be taken with other supplements or medications?
Citrulline is generally safe to take with other supplements or medications, but it is always best to consult with a healthcare provider to ensure there are no potential interactions. People taking medications for blood pressure or erectile dysfunction should be especially cautious when adding Citrulline to their regimen.

Is Citrulline suitable for vegetarians or vegans?
Yes, Citrulline is a vegan-friendly supplement as it is derived from natural sources and does not contain any animal products. It is an excellent option for individuals following plant-based diets who may need additional support for their exercise performance or cardiovascular health.

Is Citrulline approved by any regulatory authorities?
Citrulline is considered a safe dietary supplement by the United States Food and Drug Administration (FDA) and other regulatory authorities. However, it is always essential to choose high-quality supplements from reputable brands to ensure purity and potency.

How long does it take to see results from Citrulline supplementation?
The time it takes to see results from Citrulline supplementation can vary depending on individual factors such as dosage, diet, exercise routine, and overall health. Some people may notice improved performance and endurance within a few weeks of starting Citrulline supplementation, while others may take longer. Consistency is key to experiencing the full benefits of Citrulline.
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